The first episode of "Prison Break," titled "Pilot," premiered on August 29, 2005. The episode introduces the main characters and sets the stage for the series.
"Pilot" Air Date: August 29, 2005
If your downloaded subtitles are ahead or behind by 3 seconds, do not download a new file. Use a media player with a subtitle offset feature: Prison Break English Subtitles Season 1 Episode 1